Symptoms

Of

 

Ochratoxin Mycotoxin

Exposure

 

With

Bibliography

 

(HOME) 

 

Compiled by

Deborah Cazden

July 9, 2001

 

 

Sources:

 Aerotech Laboratories

Mycotoxin Prevention and Control in Foodgrains

PubMed

 

Please feel free to use this resource.

All I ask is to please keep my name on it, present it

as a whole document, and do not use it for profit.

Thank You.

 

 

2001 Deborah Cazden

All rights reserved

dcazden@gmail.com

 

 

Disclaimer,

This document is not meant to diagnose a health problem it is simply a tool. Please consult with your regular doctor if you have a health concern. No guarantee is implied by the use of this document. All information contained here is accurate to the best of my knowledge, but since the compilation is from other sources, I cannot guarantee all the information is correct.


Symptoms of Ochratoxin exposure

 

 

 

 

 

 

 


N
A SYMPTOM (description)
M (references)
E


 

 

 

 

 

 

1.       Anemia (low red blood cell count)
(Chernozemsky et al, 1977; Huff et. al., 1979)

 

 

 

 

 

 

2.       Anorexia (loss of appetite, refusal to eat)
(Chernozemsky et al, 1977)

 

 

 

 

 

 

3.       Apoptosis (cell death)
(Gekle, 2000;
Schwerdt et. al., 1999; Schwerdt et. al. 2000)

 

 

 

 

 

 

4.       Carcinogenic (causes cancer)
(Burge and Ammann, 1999; Jakobsen, et al., 1993)

 

 

 

 

 

 

5.       Copper colored skin
(Chernozemsky et al, 1977)

 

 

 

 

 

 

6.       Decreased Hemoglobin
(Gupta et. al. 1979)

 

 

 

 

 

 

7.       Decreased lymphocytes (immune cells)
(
Muller, 1999; Verma and Mathew, 1998))

 

 

 

 

 

 

8.       Endemic Nephropathy
(Peraica and Domijan; 2000, Krough, 1972)

 

 

 

 

 

 

9.       Fatigue
(Chernozemsky et al, 1977)

 

 

 

 

 

 

10.   Headache
(Chernozemsky et al, 1977)

 

 

 

 

 

 

11.   Increased apoptotic phagocytes (death of neutrophils and macrophages)
(Muller, 1999)

 

 

 

 

 

 

12.   Increased clotting time
(Gupta et. al. 1979)

 

 

 

 

 

 

13.   Increased eosinophils (cells that can trigger asthma attacks and immune response)
(
Muller, 1999)

 

 

 

 

 

 

14.   Increased leukocytes (white blood cells)
(
Muller, 1999)

 

 

 

 

 

 

15.   Increased Neutrophils (a type of white blood cell)
(
Muller, 1999)


 

 

 

 

 

 

 


N
A SYMPTOM (description)
M (references)
E


 

 

 

 

 

 

16.   Increased reactive oxygen radicals (very powerful oxidizing agents that cause structural damage to proteins and nucleic acids)
(
Muller, 1999)

 

 

 

 

 

 

17.   Induces DNA adducts (may cause mutations in DNA) (leads to nucleotide substitutions, deletions, and chromosome rearrangements)
(Burge and Ammann, 1999; Jakobsen, et al., 1993)

 

 

 

 

 

 

18.   Inhibition of protein synthesis
(Burge and Ammann, 1999; Jakobsen, et al., 1993)

 

 

 

 

 

 

19.   Inhibits Phenylalanine hydroxylase
(Zanic-Grubisic T, et al., 2000)

 

 

 

 

 

 

20.   Intermittent hematuria (blood in the urine)
(Chernozemsky et al, 1977)

 

 

 

 

 

 

21.   Lassitude (fatigue)
(Chernozemsky et al, 1977)

 

 

 

 

 

 

22.   Nephrotoxic (causes kidney damage)
(Burge and Ammann, 1999; Jakobsen, et al., 1993)

 

 

 

 

 

 

23.   Neurotoxin (damages parts of the brain) (esp. ventral mesencephalon and the cerebellum)
(Belmadani A, et. al. 1999)

 

 

 

 

 

 

24.   Reduced phagocytosis (cells have a reduced ability to kill microorganisms in the body)
(
Muller, 1999)

 

 

 

 

 

 

25.   Suppresses the immune system
(
Baudrimont, et al., 1994)

 

 

 

 

 

 

26.   Teratogenic (causes birth defects)
(Zanic-Grubisic T, et al., 2000)

 

 

 

 

 

 

27.   Urinary tract tumors
(Chernozemsky et al, 1977)

 

 

 

 

 

 

28.   Yellow palms
(Chernozemsky et al, 1977)